Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
LOC102362470Kruppel-like factor 17. (428 aa)    
Predicted Functional Partners:
DAW1
Dynein assembly factor with WD repeats 1.
      
 0.634
LOC102362664
POU domain protein.
    
 0.508
HUWE1
HECT, UBA and WWE domain containing E3 ubiquitin protein ligase 1.
    
 0.476
ITPRID2
ITPR interacting domain containing 2.
      
 0.474
CREBBP
CREB binding protein.
    
 0.452
LOC102352539
Uncharacterized protein.
    
 0.445
H2ZU49_LATCH
Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium.
    
 0.431
GATA6
GATA binding protein 6.
    
 0.431
LOC102367479
Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium.
    
 0.431
SLC17A5
Solute carrier family 17 member 5.
      
 0.427
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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