Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SNX25Sorting nexin 25. (620 aa)    
Predicted Functional Partners:
CCDC177
Uncharacterized protein.
     
 0.806
VAPB
VAMP associated protein B and C.
    
 
 0.653
RAB33A
RAB33A, member RAS oncogene family.
      
 0.636
SNX14
Sorting nexin 14.
   
 
 0.633
H3ABC7_LATCH
Rho GTPase activating protein 33.
      
 0.629
RAPGEF2
Rap guanine nucleotide exchange factor 2.
      
 0.606
H3ANY8_LATCH
Ig-like domain-containing protein; Belongs to the MHC class I family.
      
 0.602
ANKRD10
Ankyrin repeat domain 10.
      
 0.591
RNMT
mRNA cap guanine-N7 methyltransferase.
      
 0.588
SNAPC3
Small nuclear RNA activating complex polypeptide 3.
      
 0.583
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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