STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GBX2Gastrulation brain homeobox 2. (344 aa)    
Predicted Functional Partners:
WNT1
Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.
   
 
 0.747
FGF8
Fibroblast growth factor; Belongs to the heparin-binding growth factors family.
   
 
 0.737
LOC102363544
Uncharacterized protein.
      
 0.625
ANAPC1
Anaphase promoting complex subunit 1.
      
 0.617
NEK2
NIMA related kinase 2.
      
 0.581
PAX2
Paired box 2.
    
 
 0.528
IRX3
Iroquois homeobox 3.
   
 0.484
BTBD9
BTB domain containing 9.
      
 0.468
LOC102357108
Opsin 1 (cone pigments), short-wave-sensitive 2.
      
 0.449
OTX2
Orthodenticle homeobox 2.
      
0.445
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.