Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PRF1Uncharacterized protein. (546 aa)    
Predicted Functional Partners:
LOC102367350
Fibronectin type-III domain-containing protein.
   
  
 0.923
FASLG
Fas ligand.
   
 
 0.831
CD247
CD247 molecule.
   
  
 0.778
TBX21
T-box transcription factor 21.
   
  
 0.705
EOMES
Eomesodermin.
   
 
 0.665
C9
Complement C9.
     
0.652
LAMP1
Lysosomal associated membrane protein 1.
      
 0.641
DENND2B
Suppression of tumorigenicity 5.
      
 0.627
GZMK
Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family.
   
 0.621
STX11
Syntaxin 11; Belongs to the syntaxin family.
     
 0.619
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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