Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
PDK2Protein-serine/threonine kinase. (540 aa)    
Predicted Functional Partners:
PDHB
Pyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.
    
 0.954
PDHX
Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex.
    
 0.900
PDHA1
Pyruvate dehydrogenase E1 component subunit alpha; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
   
 0.894
DLAT
Acetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
    
 0.890
PDK3
Protein-serine/threonine kinase.
   
  0.871
DLD
Dihydrolipoamide dehydrogenase.
   
 0.838
H3AIU3_LATCH
Dihydrolipoamide dehydrogenase.
   
 0.764
CLPP
ATP-dependent Clp protease proteolytic subunit.
   
 0.752
ECI1
Enoyl-CoA delta isomerase 1; Belongs to the enoyl-CoA hydratase/isomerase family.
   
 0.712
CS
Citrate synthase; Belongs to the citrate synthase family.
   
 0.697
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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