STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SERPINE1Serpin family E member 1; Belongs to the serpin family. (403 aa)    
Predicted Functional Partners:
VTN
Vitronectin b.
   
 0.997
PLAU
Uncharacterized protein.
   
 0.991
PLAT
Plasminogen activator; Belongs to the peptidase S1 family.
   
 0.989
SERPINE2
Serpin family E member 2; Belongs to the serpin family.
  
  
 
0.666
LOC102356587
Uncharacterized protein; Belongs to the peptidase S1 family. Plasminogen subfamily.
    
 0.627
PLG
Plasminogen; Belongs to the peptidase S1 family. Plasminogen subfamily.
    
 0.627
H3A3Z8_LATCH
SERPIN domain-containing protein; Belongs to the serpin family.
  
 
 
 0.597
IL6
Uncharacterized protein.
   
 
 0.577
RETN
Uncharacterized protein.
     
 0.566
LEP
Leptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. Belongs to the leptin family.
      
 0.558
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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