Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
FAM83CFamily with sequence similarity 83 member C. (525 aa)    
Predicted Functional Partners:
UQCC2
Ubiquinol-cytochrome c reductase complex assembly factor 2.
   
 0.826
TTBK2
Tau tubulin kinase 2.
    
 
 0.794
RBM33
RNA binding motif protein 33.
      
 0.786
PGBD5
PiggyBac transposable element derived 5.
      
 0.744
CLMP
CXADR like membrane protein.
      
 0.738
SAMD11
Sterile alpha motif domain containing 11.
      
 0.735
STARD13
StAR related lipid transfer domain containing 13.
      
 0.729
CYTB
Cytochrome b; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain. The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c. Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
    
 0.722
ARID3B
AT-rich interaction domain 3B.
      
 0.705
AKR7L
Aldo-keto reductase family 7 like (gene/pseudogene).
    
   0.702
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
Server load: low (20%) [HD]