STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CPSF7Cleavage and polyadenylation specific factor 7. (449 aa)    
Predicted Functional Partners:
NUDT21
Cleavage and polyadenylation specificity factor subunit 5; Component of the cleavage factor Im (CFIm) complex that functions as an activator of the pre-mRNA 3'-end cleavage and polyadenylation processing required for the maturation of pre-mRNA into functional mRNAs. CFIm contributes to the recruitment of multiprotein complexes on specific sequences on the pre-mRNA 3'-end, so called cleavage and polyadenylation signals (pA signals). Most pre-mRNAs contain multiple pA signals, resulting in alternative cleavage and polyadenylation (APA) producing mRNAs with variable 3'-end formation. The [...]
   
 0.997
CPSF6
Cleavage and polyadenylation specific factor 6.
  
0.987
CPSF2
Cleavage and polyadenylation specificity factor subunit 2.
   
 0.944
CPSF3
Cleavage and polyadenylation specific factor 3.
   
 0.912
CSTF2
Cleavage stimulation factor subunit 2.
   
 0.902
CPSF1
Cleavage and polyadenylation specific factor 1.
   
 0.898
CPSF4
Cleavage and polyadenylation specific factor 4.
   
 0.891
PCF11
PCF11 cleavage and polyadenylation factor subunit.
    
 0.890
U2AF2
U2 snRNP auxiliary factor large subunit; Necessary for the splicing of pre-mRNA. Belongs to the splicing factor SR family.
   
 0.879
CSTF1
Cleavage stimulation factor subunit 1.
    
 0.854
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.