Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
NHEJ1Uncharacterized protein. (303 aa)    
Predicted Functional Partners:
LIG4
DNA ligase.
    
 0.998
XRCC5
X-ray repair cross complementing 5.
    
 0.996
PRKDC
Protein kinase, DNA-activated, catalytic subunit; Belongs to the PI3/PI4-kinase family.
    
 0.990
XRCC6
X-ray repair cross complementing 6.
    
 0.973
DCLRE1C
DNA cross-link repair 1C.
     
 0.910
XRCC4
X-ray repair cross complementing 4.
     
 0.866
POLL
DNA polymerase lambda; Belongs to the DNA polymerase type-X family.
     
 0.825
DNTT
DNA-directed DNA/RNA polymerase mu; Gap-filling polymerase involved in repair of DNA double- strand breaks by non-homologous end joining (NHEJ). Belongs to the DNA polymerase type-X family.
     
 0.792
ATM
ATM serine/threonine kinase.
    
 
 0.719
ALKBH8
AlkB homolog 8, tRNA methyltransferase.
      
 0.681
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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