STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NHEJ1Uncharacterized protein. (303 aa)    
Predicted Functional Partners:
XRCC5
X-ray repair cross complementing 5.
    
 0.988
LIG4
DNA ligase.
    
 0.985
XRCC6
X-ray repair cross complementing 6.
    
 0.974
PRKDC
Protein kinase, DNA-activated, catalytic subunit; Belongs to the PI3/PI4-kinase family.
    
 0.974
DCLRE1C
DNA cross-link repair 1C.
   
 
 0.820
XRCC4
X-ray repair cross complementing 4.
     
 0.749
DNTT
DNA-directed DNA/RNA polymerase mu; Gap-filling polymerase involved in repair of DNA double- strand breaks by non-homologous end joining (NHEJ). Belongs to the DNA polymerase type-X family.
     
 0.735
POLL
DNA polymerase lambda; Belongs to the DNA polymerase type-X family.
     
 0.734
H3ALV1_LATCH
Uncharacterized protein.
    
 0.645
H2ZTC3_LATCH
PARP-type domain-containing protein.
    
 0.609
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.