STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GHRGrowth hormone receptor. (543 aa)    
Predicted Functional Partners:
LOC102349296
Uncharacterized protein.
    
 0.988
H3B4D3_LATCH
Somatolactin alpha.
    
 0.988
JAK2
Tyrosine-protein kinase.
    
 0.892
LOC102363504
Tyrosine-protein kinase.
    
 0.863
SOCS2
Suppressor of cytokine signaling 2.
    
 0.822
PRL
Prolactin.
     
 0.756
LOC102348150
Signal transducer and activator of transcription.
    
 0.705
CYTB
Cytochrome b; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain. The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c. Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
      
 0.696
H2ZYR6_LATCH
FERM domain-containing protein.
    
 0.674
LOC102356003
SH2 domain-containing protein.
    
 0.674
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
Server load: medium (54%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.