STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DBR1Debranching RNA lariats 1. (542 aa)    
Predicted Functional Partners:
DHX38
DEAH-box helicase 38.
    
 
 0.860
XPO5
Exportin 5.
   
  
 0.712
CWF19L1
CWF19 like cell cycle control factor 1.
   
 
 0.678
LOC102352135
Uncharacterized protein.
   
 
0.673
PRPF18
PRP18 pre-mRNA processing factor 18 homolog (yeast).
    
 
 0.616
DROSHA
Drosha ribonuclease III.
   
  
 0.614
SNRPC
U1 small nuclear ribonucleoprotein C; Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. SNRPC/U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing. The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA. Stimulates commitment or early (E) complex formation by stabilizing the base pairing of the 5' end of the U1 snRNA and the 5' splice-site region. Belongs to the U1 [...]
      
 0.599
DICER1
Dicer 1, ribonuclease III; Belongs to the helicase family. Dicer subfamily.
   
  
 0.566
CWF19L2
CWF19 like cell cycle control factor 2.
   
  
 0.566
XAB2
XPA binding protein 2.
   
  
 0.562
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
Server load: low (34%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.