Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
H3A9E2_LATCHUncharacterized protein. (1114 aa)    
Predicted Functional Partners:
HSPG2
Heparan sulfate proteoglycan 2.
   
 0.761
FBLN1
Fibulin-1; Incorporated into fibronectin-containing matrix fibers. May play a role in cell adhesion and migration along protein fibers within the extracellular matrix (ECM). Could be important for certain developmental processes and contribute to the supramolecular organization of ECM architecture, in particular to those of basement membranes.
   
 0.700
VTN
Vitronectin b.
    
 0.604
MFAP2
Microfibril associated protein 2.
   
 0.599
LOC102349388
Uncharacterized protein.
   
 
 0.546
NUDCD1
NudC domain containing 1.
    
   0.525
LOC102356940
Xin actin binding repeat containing 1.
    
 0.498
TMEM43
Transmembrane protein 43.
    
 
 0.474
LOXL1
Lysyl oxidase like 1.
   
  
 0.467
EFEMP1
EGF containing fibulin extracellular matrix protein 1.
   
  0.454
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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