STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PNPLA1PNPLA domain-containing protein. (376 aa)    
Predicted Functional Partners:
ABHD5
Abhydrolase domain containing 5.
    
 
 0.768
LIPE
Lipase E, hormone sensitive type.
   
 
 0.712
LIPA
Lipase; Belongs to the AB hydrolase superfamily. Lipase family.
    
 
 0.488
PNPLA8
Patatin like phospholipase domain containing 8.
      
 0.465
SAMM50
SAMM50 sorting and assembly machinery component.
 
    
 0.456
FASN
Fatty acid synthase.
   
  
 0.453
MBOAT7
Membrane bound O-acyltransferase domain containing 7; Belongs to the membrane-bound acyltransferase family.
      
 0.449
NIPAL4
NIPA like domain containing 4.
      
 0.438
ASMTL
Acetylserotonin O-methyltransferase like.
   
  
 0.435
LDLRAP1
Low density lipoprotein receptor adaptor protein 1b.
      
 0.418
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.