GAK protein (Latimeria chalumnae) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

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textmining

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experimentally determined

co-expression

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gene neighborhood

gene co-occurrence

gene fusions

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[Homology]

Score

GAK

J domain-containing protein. (289 aa)

Predicted Functional Partners:

CLTCL1

0.993

CLTC

0.993

CLHC1

0.993

CLTA

0.990

DNAJC6

0.990

CLTB

0.990

HIP1R

0.990

HIP1

0.990

CLINT1

0.976

DNM1

0.973

Your Current Organism:

Latimeria chalumnae

NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth

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structured XML interaction data, according to the 'PSI-MI' data standard

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node degree of proteins in your network (given the current score cut-off)

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... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CLHC1	CLINT1	ENSLACP00000022627	ENSLACP00000017778	Clathrin heavy chain linker domain-containing protein 1.	Clathrin interactor 1.	0.632
CLHC1	CLTA	ENSLACP00000022627	ENSLACP00000001828	Clathrin heavy chain linker domain-containing protein 1.	Clathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family.	0.831
CLHC1	CLTB	ENSLACP00000022627	ENSLACP00000016980	Clathrin heavy chain linker domain-containing protein 1.	Clathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family.	0.831
CLHC1	DNAJC6	ENSLACP00000022627	ENSLACP00000004567	Clathrin heavy chain linker domain-containing protein 1.	DnaJ heat shock protein family (Hsp40) member C6.	0.973
CLHC1	DNM1	ENSLACP00000022627	ENSLACP00000019721	Clathrin heavy chain linker domain-containing protein 1.	Dynamin 1; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	0.653
CLHC1	GAK	ENSLACP00000022627	ENSLACP00000006296	Clathrin heavy chain linker domain-containing protein 1.	J domain-containing protein.	0.993
CLHC1	HIP1	ENSLACP00000022627	ENSLACP00000021547	Clathrin heavy chain linker domain-containing protein 1.	Huntingtin interacting protein 1.	0.794
CLHC1	HIP1R	ENSLACP00000022627	ENSLACP00000020325	Clathrin heavy chain linker domain-containing protein 1.	Huntingtin interacting protein 1 related.	0.794
CLINT1	CLHC1	ENSLACP00000017778	ENSLACP00000022627	Clathrin interactor 1.	Clathrin heavy chain linker domain-containing protein 1.	0.632
CLINT1	CLTA	ENSLACP00000017778	ENSLACP00000001828	Clathrin interactor 1.	Clathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family.	0.930
CLINT1	CLTB	ENSLACP00000017778	ENSLACP00000016980	Clathrin interactor 1.	Clathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family.	0.869
CLINT1	CLTC	ENSLACP00000017778	ENSLACP00000011035	Clathrin interactor 1.	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family.	0.868
CLINT1	CLTCL1	ENSLACP00000017778	ENSLACP00000010273	Clathrin interactor 1.	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family.	0.868
CLINT1	DNAJC6	ENSLACP00000017778	ENSLACP00000004567	Clathrin interactor 1.	DnaJ heat shock protein family (Hsp40) member C6.	0.841
CLINT1	GAK	ENSLACP00000017778	ENSLACP00000006296	Clathrin interactor 1.	J domain-containing protein.	0.976
CLINT1	HIP1	ENSLACP00000017778	ENSLACP00000021547	Clathrin interactor 1.	Huntingtin interacting protein 1.	0.508
CLINT1	HIP1R	ENSLACP00000017778	ENSLACP00000020325	Clathrin interactor 1.	Huntingtin interacting protein 1 related.	0.643
CLTA	CLHC1	ENSLACP00000001828	ENSLACP00000022627	Clathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family.	Clathrin heavy chain linker domain-containing protein 1.	0.831
CLTA	CLINT1	ENSLACP00000001828	ENSLACP00000017778	Clathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family.	Clathrin interactor 1.	0.930
CLTA	CLTB	ENSLACP00000001828	ENSLACP00000016980	Clathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family.	Clathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family.	0.901