Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ROBO2Roundabout guidance receptor 2. (1213 aa)    
Predicted Functional Partners:
LOC102357836
Ig-like domain-containing protein.
 
     
0.899
H3AM86_LATCH
Uncharacterized protein.
 
      0.899
LOC106705389
Roundabout, axon guidance receptor, homolog 2 (Drosophila).
 
     
0.899
SLIT1
Slit guidance ligand 1.
   
 0.856
SLIT3
Slit guidance ligand 3.
   
 0.843
H3AC70_LATCH
LRRNT domain-containing protein.
   
 0.757
SLIT2
Slit guidance ligand 2.
   
 0.757
H3BCU0_LATCH
LRRNT domain-containing protein.
   
 0.650
NYX
Nyctalopin.
   
 0.636
GDNF
Glial cell derived neurotrophic factor.
     
 0.600
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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