Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
ISLRImmunoglobulin superfamily containing leucine rich repeat. (673 aa)    
Predicted Functional Partners:
BRINP3
BMP/retinoic acid inducible neural specific 3.
   
  
 0.834
STOML1
Stomatin like 1.
   
 
 0.831
SAE1
SUMO1 activating enzyme subunit 1.
     
 0.698
G3BP1
G3BP stress granule assembly factor 1.
    
 
 0.688
CDH12
Cadherin 12; Cadherins are calcium-dependent cell adhesion proteins.
     
 0.560
SAMHD1
Uncharacterized protein.
      
 0.553
CGAS
Cyclic GMP-AMP synthase.
      
 0.512
F5
Coagulation factor V; Belongs to the multicopper oxidase family.
     
  0.491
BHLHE22
Basic helix-loop-helix family member e22.
   
  
 0.481
LRRC40
Leucine rich repeat containing 40.
    
 
 0.471
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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