TAGAP protein (Latimeria chalumnae) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

TAGAP

T cell activation RhoGTPase activating protein. (711 aa)

Predicted Functional Partners:

RIPOR3

0.835

LOC102349977

0.793

IRF2BPL

0.650

RSPH3

0.639

SNTA1

0.637

GJD4

0.623

RIPOR2

0.605

SH2B3

0.598

ANKDD1A

0.587

RIPOR1

0.584

Your Current Organism:

Latimeria chalumnae

NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc.

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ANKDD1A	TAGAP	ENSLACP00000001997	ENSLACP00000006313	Ankyrin repeat and death domain containing 1A.	T cell activation RhoGTPase activating protein.	0.587
GJD4	TAGAP	ENSLACP00000002846	ENSLACP00000006313	Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.	T cell activation RhoGTPase activating protein.	0.623
IRF2BPL	TAGAP	ENSLACP00000021461	ENSLACP00000006313	Interferon regulatory factor 2 binding protein like.	T cell activation RhoGTPase activating protein.	0.650
LOC102349977	RIPOR1	ENSLACP00000000458	ENSLACP00000008843	Uncharacterized protein.	RHO family interacting cell polarization regulator 1.	0.474
LOC102349977	RIPOR2	ENSLACP00000000458	ENSLACP00000007224	Uncharacterized protein.	RHO family interacting cell polarization regulator 2.	0.474
LOC102349977	RIPOR3	ENSLACP00000000458	ENSLACP00000007409	Uncharacterized protein.	RIPOR family member 3.	0.795
LOC102349977	TAGAP	ENSLACP00000000458	ENSLACP00000006313	Uncharacterized protein.	T cell activation RhoGTPase activating protein.	0.793
RIPOR1	LOC102349977	ENSLACP00000008843	ENSLACP00000000458	RHO family interacting cell polarization regulator 1.	Uncharacterized protein.	0.474
RIPOR1	TAGAP	ENSLACP00000008843	ENSLACP00000006313	RHO family interacting cell polarization regulator 1.	T cell activation RhoGTPase activating protein.	0.584
RIPOR2	LOC102349977	ENSLACP00000007224	ENSLACP00000000458	RHO family interacting cell polarization regulator 2.	Uncharacterized protein.	0.474
RIPOR2	TAGAP	ENSLACP00000007224	ENSLACP00000006313	RHO family interacting cell polarization regulator 2.	T cell activation RhoGTPase activating protein.	0.605
RIPOR3	LOC102349977	ENSLACP00000007409	ENSLACP00000000458	RIPOR family member 3.	Uncharacterized protein.	0.795
RIPOR3	TAGAP	ENSLACP00000007409	ENSLACP00000006313	RIPOR family member 3.	T cell activation RhoGTPase activating protein.	0.835
RSPH3	TAGAP	ENSLACP00000003139	ENSLACP00000006313	Radial spoke head 3.	T cell activation RhoGTPase activating protein.	0.639
SH2B3	TAGAP	ENSLACP00000015000	ENSLACP00000006313	SH2B adaptor protein 3.	T cell activation RhoGTPase activating protein.	0.598
SNTA1	TAGAP	ENSLACP00000012467	ENSLACP00000006313	Syntrophin alpha 1.	T cell activation RhoGTPase activating protein.	0.637
TAGAP	ANKDD1A	ENSLACP00000006313	ENSLACP00000001997	T cell activation RhoGTPase activating protein.	Ankyrin repeat and death domain containing 1A.	0.587
TAGAP	GJD4	ENSLACP00000006313	ENSLACP00000002846	T cell activation RhoGTPase activating protein.	Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.	0.623
TAGAP	IRF2BPL	ENSLACP00000006313	ENSLACP00000021461	T cell activation RhoGTPase activating protein.	Interferon regulatory factor 2 binding protein like.	0.650
TAGAP	LOC102349977	ENSLACP00000006313	ENSLACP00000000458	T cell activation RhoGTPase activating protein.	Uncharacterized protein.	0.793