Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LAMP2Lysosomal associated membrane protein 2. (416 aa)    
Predicted Functional Partners:
LAMP1
Lysosomal associated membrane protein 1.
  
0.997
TMEM192
Transmembrane protein 192.
    
 0.980
GORASP2
Golgi reassembly stacking protein 2.
    
 0.903
TFEB
Transcription factor EB.
   
 
 0.886
BECN1
Beclin 1, autophagy related.
      
 0.872
CD63
Tetraspanin.
   
 0.856
ATG5
Autophagy protein 5; Involved in autophagic vesicle formation.
      
 0.846
EEA1
Early endosome antigen 1.
      
 0.793
SNCA
Gamma-synuclein; Belongs to the synuclein family.
   
 
 0.787
CTSB
Cathepsin B; Belongs to the peptidase C1 family.
   
 
 0.778
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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