Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
GCSHGlycine cleavage system H protein; The H protein shuttles the methylamine group of glycine from the P protein to the T protein; Belongs to the GcvH family. (177 aa)    
Predicted Functional Partners:
GLDC
Glycine cleavage system P protein; The glycine cleavage system catalyzes the degradation of glycine.
 
 0.999
AMT
Aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine; Belongs to the GcvT family.
 
 0.999
LIPT2
Putative lipoyltransferase 2, mitochondrial; Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate- dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate. Belongs to the LipB family.
  
 0.990
H3AIU3_LATCH
Dihydrolipoamide dehydrogenase.
 
 
 0.990
SHMT1
Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family.
  
 
 0.989
LIPT1
Lipoyltransferase 1.
   
 0.989
SHMT2
Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family.
  
 
 0.989
MTHFR
Methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family.
    
 0.987
MTHFD2L
Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2 like.
  
 
 0.983
MTHFD2
Uncharacterized protein.
  
 
 0.983
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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