Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
TERF2Telomeric repeat-binding factor; Binds the telomeric double-stranded 5'-TTAGGG-3' repeat. (489 aa)    
Predicted Functional Partners:
TERF2IP
TERF2 interacting protein.
    
 0.916
POT1
Protection of telomeres 1.
    
 0.891
TEN1
TEN1 subunit of CST complex.
     
  0.610
ZNF276
Zinc finger protein 276.
    
 0.603
TERF1
Telomeric repeat binding factor 1.
     
0.587
H2ZWI5_LATCH
Uncharacterized protein.
    
 0.538
XRCC6
X-ray repair cross complementing 6.
    
 
 0.526
H3ADV1_LATCH
Telomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. It elongates telomeres. It is a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme.
    
 0.521
TUBE1
Tubulin epsilon 1; Belongs to the tubulin family.
      
 0.511
DCLRE1B
DNA cross-link repair 1B.
    
 
 0.510
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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