Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
VPS36Vacuolar protein sorting 36 homolog. (261 aa)    
Predicted Functional Partners:
CHMP6
Charged multivesicular body protein 6.
    
 0.999
SNF8
Vacuolar-sorting protein SNF8; Component of the endosomal sorting complex required for transport II (ESCRT-II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs. Belongs to the SNF8 family.
   
 0.999
VPS28
VPS28 subunit of ESCRT-I; Belongs to the VPS28 family.
    
 0.997
TSG101
Tumor susceptibility 101.
    
 0.994
VPS37A
VPS37A subunit of ESCRT-I.
    
 0.986
RPS27A
Ribosomal protein S27a.
    
 0.973
CHMP2A
Charged multivesicular body protein 2A.
    
 0.970
VPS37C
VPS37 C-terminal domain-containing protein.
    
 0.945
CHMP4A
Charged multivesicular body protein 4A.
    
 0.944
CHMP4B
Charged multivesicular body protein 4B.
    
 0.944
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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