Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
RPS6KA3Ribosomal protein S6 kinase A3. (709 aa)    
Predicted Functional Partners:
LOC102354262
Mitogen-activated protein kinase.
   
0.971
MAPK1
Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.
   
0.971
TSC2
TSC complex subunit 2.
    
 0.950
ATF4
Activating transcription factor 4.
    
 0.931
TSC1
TSC complex subunit 1.
    
 0.928
TBC1D7
TBC1 domain family member 7.
     
 0.911
BUB1
BUB1 mitotic checkpoint serine/threonine kinase.
     
  0.900
PKMYT1
Protein kinase, membrane associated tyrosine/threonine 1.
     
 
0.900
LOC102365238
Ribosomal protein S6 kinase.
   
  0.892
CREB1
cAMP responsive element binding protein 1.
   
 0.812
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
Server load: low (12%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.