STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CDKN2CCyclin dependent kinase inhibitor 2C. (169 aa)    
Predicted Functional Partners:
CDK6
Cyclin dependent kinase 6; Belongs to the protein kinase superfamily.
   
 0.986
CDK4
Cyclin dependent kinase 4; Belongs to the protein kinase superfamily.
   
 0.986
LOC102366718
Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.
   
 0.986
CCND1
Cyclin D1; Belongs to the cyclin family.
    
 0.975
LOC102345953
Cyclin D3; Belongs to the cyclin family.
    
 0.969
LOC102367471
Uncharacterized protein; Belongs to the cyclin family.
    
 0.952
CCND2
Cyclin D2, b; Belongs to the cyclin family.
    
 0.703
CDK1
Cyclin dependent kinase 1; Belongs to the protein kinase superfamily.
   
 0.702
LOC102367189
Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.
   
 0.698
CDK2
Cyclin dependent kinase 2; Belongs to the protein kinase superfamily.
   
 0.698
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.