STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LYNTyrosine-protein kinase. (515 aa)    
Predicted Functional Partners:
SYK
Tyrosine-protein kinase.
  
0.909
PAG1
Phosphoprotein membrane anchor with glycosphingolipid microdomains 1.
    
 0.849
CSF3R
Colony stimulating factor 3 receptor.
   
 0.839
CD79A
CD79a molecule, immunoglobulin-associated alpha.
   
 0.816
LCP2
Lymphocyte cytosolic protein 2.
   
 0.798
GRB2
Growth factor receptor bound protein 2.
   
0.792
INPP5D
Inositol polyphosphate-5-phosphatase D.
   
 0.788
PTPN6
Protein tyrosine phosphatase non-receptor type 6.
   
 0.787
ZAP70
Tyrosine-protein kinase.
  
0.783
STAT3
Signal transducer and activator of transcription.
   
 0.783
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.