STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
IRF5Interferon regulatory factor 5. (515 aa)    
Predicted Functional Partners:
TRAF6
TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.
   
 0.971
LOC102352351
C-C motif chemokine.
   
 
 0.903
MYD88
Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response.
   
 0.789
IKBKE
Inhibitor of nuclear factor kappa B kinase subunit epsilon.
   
 0.621
TLR3
Toll like receptor 3; Belongs to the Toll-like receptor family.
   
 
 0.564
IFNAR1
Uncharacterized protein.
   
  
 0.543
RDH16
Retinol dehydrogenase 16; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
      
 0.540
TBK1
TANK binding kinase 1.
   
 0.531
IRF1
Interferon regulatory factor.
   
0.513
IL10
Interleukin 10.
   
 
 0.496
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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