Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
FAHD2AFumarylacetoacetate hydrolase domain containing 2A. (323 aa)    
Predicted Functional Partners:
HGD
Homogentisate 1,2-dioxygenase.
  
 
 0.739
LSM6
LSM6 homolog, U6 small nuclear RNA and mRNA degradation associated.
      
 0.611
IPO9
Importin 9.
      
 0.589
SORD
Sorbitol dehydrogenase.
  
 
 0.573
METTL7A
Methyltransferase like 7A.
      
 0.573
RPN2
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol- pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the en [...]
      
 0.569
RPL17
Ribosomal protein L17; Belongs to the universal ribosomal protein uL22 family.
      
 0.557
GCDH
Glutaryl-CoA dehydrogenase.
  
  
 0.554
PPIL4
Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.
      
 0.549
LOC102348996
Mago homolog, exon junction complex subunit.
      
 0.537
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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