Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LRRCC1Leucine rich repeat and coiled-coil centrosomal protein 1. (1024 aa)    
Predicted Functional Partners:
WDHD1
WD repeat and HMG-box DNA binding protein 1.
    
 
 0.795
SKA2
Spindle and kinetochore associated complex subunit 2.
      
 0.789
CENPI
Centromere protein I.
    
 
 0.704
SKA3
Spindle and kinetochore associated complex subunit 3.
   
 
 0.703
CCDC61
Uncharacterized protein.
      
 0.684
CENPN
Centromere protein N.
      
 0.663
CLASP2
Cytoplasmic linker associated protein 2.
     
 0.661
SKA1
Spindle and kinetochore associated complex subunit 1.
      
 0.655
KIF18A
Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.
    
 
 0.648
HAUS8
Uncharacterized protein.
      
 0.641
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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