Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
TECPR2Tectonin beta-propeller repeat containing 2. (1417 aa)    
Predicted Functional Partners:
VPS41
Vacuolar protein sorting-associated protein 41 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport pathways; Belongs to the VPS41 family.
   
   0.958
VPS16
Vacuolar protein sorting-associated protein 16 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes. Belongs to the VPS16 family.
    
 
 0.948
VPS18
VPS18 core subunit of CORVET and HOPS complexes.
    
   0.923
ASMTL
Acetylserotonin O-methyltransferase like.
      
 0.790
VPS33B
VPS33B late endosome and lysosome associated; Belongs to the STXBP/unc-18/SEC1 family.
    
 
 0.737
H3BFJ3_LATCH
VPS33A core subunit of CORVET and HOPS complexes; Belongs to the STXBP/unc-18/SEC1 family.
    
 
 0.737
HPS6
HPS6 biogenesis of lysosomal organelles complex 2 subunit 3.
    
 
 0.691
HPS3
HPS3 biogenesis of lysosomal organelles complex 2 subunit 1.
   
 
 0.671
TRAPPC11
Trafficking protein particle complex 11.
      
 0.635
PLA2G6
Phospholipase A2 group VI.
      
 0.633
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.