Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
MCCC2Methylcrotonoyl-CoA carboxylase 2. (285 aa)    
Predicted Functional Partners:
MCCC1
Methylcrotonoyl-CoA carboxylase 1.
 
 0.997
IVD
Isovaleryl-CoA dehydrogenase.
 
 
 0.987
PCCA
Propionyl-CoA carboxylase subunit alpha.
  
 0.969
AUH
AU RNA binding methylglutaconyl-CoA hydratase.
  
 
 0.964
ECHS1
Enoyl-CoA hydratase, short chain 1; Belongs to the enoyl-CoA hydratase/isomerase family.
  
 
 0.949
ACADM
Acyl-CoA dehydrogenase medium chain.
 
 
 0.947
HADHA
Hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha; Belongs to the enoyl-CoA hydratase/isomerase family.
  
 
 0.944
EHHADH
Enoyl-CoA hydratase and 3-hydroxyacyl CoA dehydrogenase.
  
 
 0.940
ECH1
Enoyl-CoA hydratase 1.
   
 0.920
LOC102365715
Si:ch211-198n5.11.
  
  
 
0.904
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
Server load: low (10%) [HD]