Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LOC102351641Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (975 aa)    
Predicted Functional Partners:
TRRAP
Transformation/transcription domain-associated protein.
 
  
  0.994
TADA3
Transcriptional adaptor 3.
    
 0.992
TAF10
Transcription initiation factor TFIID subunit 10; TFIID is a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors; Belongs to the TAF10 family.
    
 0.991
TADA2B
Transcriptional adapter.
    
 0.990
ING3
Inhibitor of growth protein.
   
 0.990
H3BCP3_LATCH
Uncharacterized protein.
    
 0.988
SGF29
SAGA complex associated factor 29.
    
 0.987
ATXN7L3
Ataxin-7-like protein 3; Component of the transcription regulatory histone acetylation (HAT) complex SAGA, a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates in a subcomplex that specifically deubiquitinates histone H2B. The SAGA complex is recruited to specific gene promoters by activators, where it is required for transcription.
    
 0.985
BRD8
Bromodomain containing 8.
    
 0.985
DMAP1
DNA methyltransferase 1 associated protein 1.
    
 0.984
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
Server load: low (14%) [HD]