Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
H3AA81_LATCHIntegrase catalytic domain-containing protein. (316 aa)    
Predicted Functional Partners:
H3AQ61_LATCH
Reverse transcriptase domain-containing protein.
 
 
   0.809
RBBP7
WD_REPEATS_REGION domain-containing protein.
    
 0.786
LOC102347269
Retinoblastoma binding protein 4, like.
    
 0.786
RBBP4
RB binding protein 4, chromatin remodeling factor.
    
 0.786
H3B5T7_LATCH
Uncharacterized protein.
 
 
   0.684
HDAC3
Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily.
   
 0.632
HDAC8
Histone deacetylase 8; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.
   
 0.632
HDAC1
Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.
   
 0.632
H2ZXJ5_LATCH
Uncharacterized protein.
 
 
   0.605
MTA3
Metastasis associated 1 family member 3.
   
 0.598
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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