Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PLEKHH1Pleckstrin homology, MyTH4 and FERM domain containing H1. (1450 aa)    
Predicted Functional Partners:
ST18
ST18 C2H2C-type zinc finger transcription factor.
   
    0.965
ANGPTL1
Angiopoietin like 1.
      
 0.655
RPS6KB1
Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.
      
 0.655
ZFYVE26
Zinc finger FYVE-type containing 26.
      
 0.589
RAD51B
RAD51 paralog B.
      
 0.525
FAM135A
Family with sequence similarity 135 member A.
      
 0.517
AREL1
Apoptosis resistant E3 ubiquitin protein ligase 1.
      
 0.503
THBS2
Uncharacterized protein.
      
 0.497
ITGA11
Integrin subunit alpha 11; Belongs to the integrin alpha chain family.
      
 0.478
FNBP1L
Formin binding protein 1 like.
      
 0.450
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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