STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PREX2Phosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 2. (1418 aa)    
Predicted Functional Partners:
CDC42
Cell division cycle 42.
    
 0.810
PTEN
Phosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family.
     
 0.615
TPTE2
Transmembrane phosphatase with tensin homology.
     
 0.615
LOC102362077
Ras homolog gene family, member Gc.
    
 0.584
RHOG
Ras homolog family member G.
    
 0.584
LOC102351732
Uncharacterized protein.
    
 0.559
RAC1
Rac family small GTPase 1.
    
 0.559
RAC3
Rac family small GTPase 3.
    
 0.559
ITSN2
Intersectin 2.
    
0.540
GNB3
G protein subunit beta 3.
    
 
 0.535
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.