Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
H3AA95_LATCHFZ domain-containing protein. (361 aa)    
Predicted Functional Partners:
ITGAV
Integrin_alpha2 domain-containing protein.
    
 0.742
MMP9
Matrix metallopeptidase 9.
   
 0.673
MMP13
Matrix metallopeptidase 13.
    
 0.648
ITGA8
Integrin subunit alpha 8; Belongs to the integrin alpha chain family.
    
 0.604
RBM20
RNA binding motif protein 20.
    
 0.604
EIF2AK3
Eukaryotic translation initiation factor 2 alpha kinase 3.
      
 0.570
H3AM01_LATCH
Integrin beta; Belongs to the integrin beta chain family.
    
 0.562
LOC102348586
Nucleolin.
    
 
 0.555
LOC102347971
Uncharacterized protein.
    
 
 0.555
ECHS1
Enoyl-CoA hydratase, short chain 1; Belongs to the enoyl-CoA hydratase/isomerase family.
      
 0.543
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
Server load: low (8%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.