Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
LOC102352162Uncharacterized protein. (645 aa)    
Predicted Functional Partners:
NDUFAF1
NADH:ubiquinone oxidoreductase complex assembly factor 1.
   
 0.846
ECI2
Enoyl-CoA delta isomerase 2.
  
 0.845
ECSIT
ECSIT signalling integrator.
   
 0.821
HSDL2
Hydroxysteroid dehydrogenase like 2.
  
 0.771
TIMMDC1
Translocase of inner mitochondrial membrane domain containing 1.
    
 0.757
NDUFS2
NADH:ubiquinone oxidoreductase core subunit S2; Belongs to the complex I 49 kDa subunit family.
   
 0.750
HADH
Hydroxyacyl-CoA dehydrogenase.
  
 0.728
ND6
NADH-ubiquinone oxidoreductase chain 6; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity).
    
 0.718
ITSN2
Intersectin 2.
    
   0.711
NDUFS3
NADH:ubiquinone oxidoreductase core subunit S3.
   
 0.704
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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