Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
SLC35E3Solute carrier family 35 member E3. (313 aa)    
Predicted Functional Partners:
NUP107
Nuclear pore complex protein; Functions as a component of the nuclear pore complex (NPC).
 
    
 0.922
SLC35C2
Solute carrier family 35 member C2.
      
 0.838
RAP1B
RAP1B, member of RAS oncogene family.
   
  
 0.732
RNF217
RBR-type E3 ubiquitin transferase.
   
  
 0.662
MDM2
E3 ubiquitin-protein ligase Mdm2; Belongs to the MDM2/MDM4 family.
 
    
 0.655
SLC35D1
Solute carrier family 35 member D1.
      
 0.641
SLC35B2
Solute carrier family 35 member B2.
      
 0.604
CDK10
Cyclin dependent kinase 10.
      
 0.582
SLC35G1
Solute carrier family 35 member G1.
      
 0.524
SLC39A11
Uncharacterized protein.
      
 0.506
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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