Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
PIM2Serine/threonine-protein kinase; Proto-oncogene with serine/threonine kinase activity involved in cell survival and cell proliferation. Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. PIM subfamily. (324 aa)    
Predicted Functional Partners:
EFNB1
Ephrin B1; Belongs to the ephrin family.
   
  
 0.646
PUF60
Poly(U) binding splicing factor 60.
      
 0.641
LRRC1
Uncharacterized protein.
    
 0.605
H3ALU1_LATCH
Uncharacterized protein.
    
 0.605
H3BA50_LATCH
Cytoplasmic polyadenylation element binding protein 1b.
      
 0.591
COPS7B
COP9 signalosome subunit 7B.
      
 0.586
GBE1
1,4-alpha-glucan branching enzyme 1.
   
  
 0.577
BICC1
BicC family RNA binding protein 1.
      
 0.560
H3B0X9_LATCH
Uncharacterized protein.
      
 0.560
FBXW11
F-box and WD repeat domain containing 11.
      
 0.555
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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