STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DUS2Dihydrouridine synthase 2. (484 aa)    
Predicted Functional Partners:
EPRS1
Glutamyl-prolyl-tRNA synthetase.
  
 
 0.991
SLC66A1L
Uncharacterized protein.
 
      0.763
TRMT5
tRNA (guanine(37)-N1)-methyltransferase; Specifically methylates the N1 position of guanosine-37 in various cytoplasmic and mitochondrial tRNAs. Methylation is not dependent on the nature of the nucleoside 5' of the target nucleoside. This is the first step in the biosynthesis of wybutosine (yW), a modified base adjacent to the anticodon of tRNAs and required for accurate decoding; Belongs to the TRM5 / TYW2 family.
   
  
 0.733
BRIX1
Biogenesis of ribosomes BRX1.
   
    0.674
DUS1L
Dihydrouridine synthase 1 like.
   
  
0.655
DDX28
DEAD-box helicase 28.
  
 
 0.649
PUS3
Pseudouridine synthase 3.
  
 
 0.643
TSR3
Probable ribosome biogenesis protein TSR3; Probable pre-rRNA processing protein involved in ribosome biogenesis.
   
  
 0.637
MAP6D1
MAP6 domain containing 1.
      
 0.627
COMTD1
Catechol-O-methyltransferase domain containing 1.
   
  
 0.624
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.