Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
OSR1Odd-skipped related transcription factor 1. (259 aa)    
Predicted Functional Partners:
SMAD6
Mothers against decapentaplegic homolog.
    
 0.630
PAX2
Paired box 2.
    
 0.625
LHX1
LIM homeobox 1.
   
 0.582
LOC102364581
Von Hippel-Lindau tumor suppressor.
    
  0.528
PAX8
Paired box 8.
    
 0.523
SPOP
Speckle type BTB/POZ protein.
   
 0.504
SMAD7
Mothers against decapentaplegic homolog.
    
 0.496
FNIP2
Folliculin interacting protein 2.
    
 0.486
EYA1
Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family.
   
 0.477
SGK3
Non-specific serine/threonine protein kinase.
    
 0.476
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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