STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GDNFGlial cell derived neurotrophic factor. (222 aa)    
Predicted Functional Partners:
GFRA1
Uncharacterized protein.
    
 0.964
RET
Ret proto-oncogene; Belongs to the protein kinase superfamily. Tyr protein kinase family.
    
 0.907
LOC102359574
GDNF domain-containing protein.
  
 
 0.890
H3A586_LATCH
GDNF domain-containing protein.
    
 0.889
GFRA2
GDNF domain-containing protein.
    
 0.878
GFRAL
GDNF family receptor alpha like.
    
 0.824
GFRA3
Uncharacterized protein.
    
 0.810
LOC102352800
GDNF family receptor alpha 4a.
    
 0.802
BDNF
Brain-derived neurotrophic factor; Promotes the survival of neuronal populations that are all located either in the central nervous system or directly connected to it; Belongs to the NGF-beta family.
      
 0.767
NTRK2
Tyrosine-protein kinase receptor.
     
 0.709
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.