STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NFIL3Nuclear factor, interleukin 3 regulated. (468 aa)    
Predicted Functional Partners:
BHLHE41
Basic helix-loop-helix family member e41.
    
 0.825
NR1D1
Nuclear receptor subfamily 1 group D member 1.
   
 
 0.757
NR1D2
Nuclear receptor subfamily 1 group D member 2.
   
 0.717
PER2
PAS domain-containing protein.
   
 0.711
COX5A
Cytochrome c oxidase subunit 5A.
   
 0.687
EOMES
Eomesodermin.
    
 
 0.656
ARNTL
Aryl hydrocarbon receptor nuclear translocator like.
   
 0.654
PER3
Period circadian regulator 3.
   
 0.644
COX2
Cytochrome c oxidase subunit 2; Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol- cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and t [...]
    
 0.631
CRY2
Cryptochrome circadian regulator 2.
   
  
 0.620
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.