CTTN protein (Latimeria chalumnae) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

CTTN

Cortactin. (555 aa)

Predicted Functional Partners:

GOSR1

0.862

STX5

0.856

GOLGA2

0.828

USO1

0.826

ACBD3

0.724

LOC102360750

0.685

LOC102363109

0.685

LOC102360491

0.685

CFL2

0.666

RHOA

0.598

Your Current Organism:

Latimeria chalumnae

NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ACBD3	CTTN	ENSLACP00000002873	ENSLACP00000007534	Acyl-CoA binding domain containing 3.	Cortactin.	0.724
CFL2	CTTN	ENSLACP00000020492	ENSLACP00000007534	Cofilin 2; Belongs to the actin-binding proteins ADF family.	Cortactin.	0.666
CTTN	ACBD3	ENSLACP00000007534	ENSLACP00000002873	Cortactin.	Acyl-CoA binding domain containing 3.	0.724
CTTN	CFL2	ENSLACP00000007534	ENSLACP00000020492	Cortactin.	Cofilin 2; Belongs to the actin-binding proteins ADF family.	0.666
CTTN	GOLGA2	ENSLACP00000007534	ENSLACP00000019526	Cortactin.	Golgin A2.	0.828
CTTN	GOSR1	ENSLACP00000007534	ENSLACP00000013932	Cortactin.	Golgi SNAP receptor complex member 1; Involved in transport from the ER to the Golgi apparatus as well as in intra-Golgi transport. It belongs to a super-family of proteins called t-SNAREs or soluble NSF (N-ethylmaleimide-sensitive factor) attachment protein receptor.	0.862
CTTN	LOC102360491	ENSLACP00000007534	ENSLACP00000022302	Cortactin.	ADF-H domain-containing protein; Belongs to the actin-binding proteins ADF family.	0.685
CTTN	LOC102360750	ENSLACP00000007534	ENSLACP00000014130	Cortactin.	ADF-H domain-containing protein; Belongs to the actin-binding proteins ADF family.	0.685
CTTN	LOC102363109	ENSLACP00000007534	ENSLACP00000015488	Cortactin.	Destrin, actin depolymerizing factor; Belongs to the actin-binding proteins ADF family.	0.685
CTTN	RHOA	ENSLACP00000007534	ENSLACP00000019259	Cortactin.	Uncharacterized protein.	0.598
CTTN	STX5	ENSLACP00000007534	ENSLACP00000002784	Cortactin.	Syntaxin 5; Belongs to the syntaxin family.	0.856
CTTN	USO1	ENSLACP00000007534	ENSLACP00000006280	Cortactin.	USO1 vesicle transport factor.	0.826
GOLGA2	CTTN	ENSLACP00000019526	ENSLACP00000007534	Golgin A2.	Cortactin.	0.828
GOLGA2	GOSR1	ENSLACP00000019526	ENSLACP00000013932	Golgin A2.	Golgi SNAP receptor complex member 1; Involved in transport from the ER to the Golgi apparatus as well as in intra-Golgi transport. It belongs to a super-family of proteins called t-SNAREs or soluble NSF (N-ethylmaleimide-sensitive factor) attachment protein receptor.	0.974
GOLGA2	STX5	ENSLACP00000019526	ENSLACP00000002784	Golgin A2.	Syntaxin 5; Belongs to the syntaxin family.	0.987
GOLGA2	USO1	ENSLACP00000019526	ENSLACP00000006280	Golgin A2.	USO1 vesicle transport factor.	0.940
GOSR1	CTTN	ENSLACP00000013932	ENSLACP00000007534	Golgi SNAP receptor complex member 1; Involved in transport from the ER to the Golgi apparatus as well as in intra-Golgi transport. It belongs to a super-family of proteins called t-SNAREs or soluble NSF (N-ethylmaleimide-sensitive factor) attachment protein receptor.	Cortactin.	0.862
GOSR1	GOLGA2	ENSLACP00000013932	ENSLACP00000019526	Golgi SNAP receptor complex member 1; Involved in transport from the ER to the Golgi apparatus as well as in intra-Golgi transport. It belongs to a super-family of proteins called t-SNAREs or soluble NSF (N-ethylmaleimide-sensitive factor) attachment protein receptor.	Golgin A2.	0.974
GOSR1	STX5	ENSLACP00000013932	ENSLACP00000002784	Golgi SNAP receptor complex member 1; Involved in transport from the ER to the Golgi apparatus as well as in intra-Golgi transport. It belongs to a super-family of proteins called t-SNAREs or soluble NSF (N-ethylmaleimide-sensitive factor) attachment protein receptor.	Syntaxin 5; Belongs to the syntaxin family.	0.999
GOSR1	USO1	ENSLACP00000013932	ENSLACP00000006280	Golgi SNAP receptor complex member 1; Involved in transport from the ER to the Golgi apparatus as well as in intra-Golgi transport. It belongs to a super-family of proteins called t-SNAREs or soluble NSF (N-ethylmaleimide-sensitive factor) attachment protein receptor.	USO1 vesicle transport factor.	0.987