STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DEF8Differentially expressed in FDCP 8 homolog. (450 aa)    
Predicted Functional Partners:
PLEKHM3
Pleckstrin homology domain containing M3.
 
  
   0.896
MTHFSD
Methenyltetrahydrofolate synthetase domain containing.
      
 0.595
TCF25
Transcription factor 25.
 
    
 0.571
PDCD5
Programmed cell death 5.
      
 0.552
SAMSN1
SAM domain, SH3 domain and nuclear localization signals 1.
   
  
 0.549
H3BGP7_LATCH
Uncharacterized protein.
   
  
 0.533
ZNF276
Zinc finger protein 276.
      
 0.532
PIK3C3
Phosphatidylinositol 3-kinase catalytic subunit type 3.
    
 
 0.526
BECN1
Beclin 1, autophagy related.
    
 
 0.521
INPP5D
Inositol polyphosphate-5-phosphatase D.
   
  
 0.517
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.