STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PLECPlectin b. (4509 aa)    
Predicted Functional Partners:
H3AS61_LATCH
S10_plectin domain-containing protein.
 
    
 0.904
LOC102348511
Uncharacterized protein.
 
    
 0.894
ITGB4
Integrin beta.
  
 0.821
JUP
Junction plakoglobin.
   
 0.739
PKP1
Plakophilin 1.
   
 0.700
H3A0S9_LATCH
Uncharacterized protein; Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion.
   
 0.663
NRBP2
Nuclear receptor binding protein 2.
      
 0.644
PKP2
Uncharacterized protein.
   
 0.641
H3A7F2_LATCH
Uncharacterized protein.
 
    
 0.639
CTNNB1
Catenin beta 1.
    
 0.616
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.