STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CCNB1Cyclin B1; Belongs to the cyclin family. (404 aa)    
Predicted Functional Partners:
CDK1
Cyclin dependent kinase 1; Belongs to the protein kinase superfamily.
   
 0.998
PLK1
Serine/threonine-protein kinase PLK.
   
 0.991
FZR1
Fizzy and cell division cycle 20 related 1.
   
 0.963
CDC27
Cell division cycle 27.
   
 0.957
CDC20
Cell division cycle 20.
   
 0.936
ANAPC10
Anaphase promoting complex subunit 10.
   
 0.931
GADD45G
Growth arrest and DNA damage inducible gamma.
    
 0.922
FBXO43
F-box protein 43.
   
 
 0.916
CCNB2
Cyclin B2; Belongs to the cyclin family.
  
  
0.905
H2ZXS9_LATCH
Cyclin N-terminal domain-containing protein; Belongs to the cyclin family.
  
  
 
0.902
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.