STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HIC1HIC ZBTB transcriptional repressor 1. (666 aa)    
Predicted Functional Partners:
SIRT1
Sirtuin 1.
    
 
 0.575
CTBP2
C-terminal binding protein 2.
    
 
 0.485
CTBP1
C-terminal binding protein 1; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
    
 
 0.485
HMMR
Hyaluronan mediated motility receptor.
   
 0.481
SKA3
Spindle and kinetochore associated complex subunit 3.
      
 0.429
PIAS2
Protein inhibitor of activated STAT 2.
    
  0.422
H3AB18_LATCH
SH3 domain-containing protein.
    
 0.409
MIA3
Uncharacterized protein.
    
 0.409
LOC102350007
Small ubiquitin-related modifier.
    
  0.402
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.