STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
IL12RB2Interleukin 12 receptor subunit beta 2. (836 aa)    
Predicted Functional Partners:
JAK2
Tyrosine-protein kinase.
   
 0.781
LOC102363504
Tyrosine-protein kinase.
   
 0.781
IL6
Uncharacterized protein.
    
 0.757
IL6R
Interleukin 6 receptor.
   
 0.697
EBI3
Epstein-Barr virus induced 3.
   
 0.681
LOC102356003
SH2 domain-containing protein.
   
 0.663
JAK1
Janus kinase 1; Belongs to the protein kinase superfamily. Tyr protein kinase family.
   
 0.663
CNTFR
Ciliary neurotrophic factor receptor.
   
 0.646
H2ZYR6_LATCH
FERM domain-containing protein.
   
 0.595
CNTF
Uncharacterized protein.
    
 0.555
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.