STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TARBP2TARBP2 subunit of RISC loading complex. (336 aa)    
Predicted Functional Partners:
DICER1
Dicer 1, ribonuclease III; Belongs to the helicase family. Dicer subfamily.
    
 0.974
DROSHA
Drosha ribonuclease III.
    
 0.862
H2ZVK6_LATCH
Uncharacterized protein; Belongs to the argonaute family.
    
 0.847
AGO4
Protein argonaute-4; Required for RNA-mediated gene silencing (RNAi). Binds to short RNAs such as microRNAs (miRNAs) and represses the translation of mRNAs which are complementary to them. Lacks endonuclease activity and does not appear to cleave target mRNAs; Belongs to the argonaute family. Ago subfamily.
    
 0.805
AGO1
Argonaute RISC component 1; Belongs to the argonaute family.
    
 0.805
MRPL44
Mitochondrial ribosomal protein L44.
    
 0.784
UEVLD
UEV domain-containing protein.
   
 
 0.706
DGCR8
DGCR8 microprocessor complex subunit.
    
 0.655
EIF2AK2
Protein kinase domain-containing protein.
    
 
 0.605
RBL1
RB transcriptional corepressor like 1.
      
 0.537
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.