STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HSPB1Heat shock protein family B (small) member 1; Belongs to the small heat shock protein (HSP20) family. (219 aa)    
Predicted Functional Partners:
MAPKAPK3
MAPK activated protein kinase 3; Belongs to the protein kinase superfamily.
   
 0.994
MAPKAPK5
MAPK activated protein kinase 5.
    
 0.992
MAPKAPK2
MAPK activated protein kinase 2.
   
 0.984
EIF4G1
Eukaryotic translation initiation factor 4 gamma 1.
    
 0.872
CRYAB
Crystallin alpha B; Belongs to the small heat shock protein (HSP20) family.
   
0.870
BAG3
BCL2 associated athanogene 3.
   
 
 0.805
LOC102363280
Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.
   
 
 0.766
HSPA4
Heat shock protein family A (Hsp70) member 4.
   
 0.760
DAXX
Death-domain associated protein.
    
 
 0.746
HSPB8
Heat shock protein family B (small) member 8; Belongs to the small heat shock protein (HSP20) family.
   
 
0.743
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.