STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
STSSteroid sulfatase. (471 aa)    
Predicted Functional Partners:
SULT2B1
Sulfotransferase; Belongs to the sulfotransferase 1 family.
   
 
 0.920
ARSI
Arylsulfatase family member I.
  
 0.913
LOC102345588
Hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1; Belongs to the 3-beta-HSD family.
    
 0.912
LOC102363673
Sulfotransferase; Belongs to the sulfotransferase 1 family.
   
 
 0.911
LOC102346130
Uncharacterized protein; Belongs to the cytochrome P450 family.
     
 0.904
LOC102365730
Uncharacterized protein; Belongs to the cytochrome P450 family.
   
 
 0.903
LOC102357693
Cytochrome P450, family 1, subfamily A; Belongs to the cytochrome P450 family.
   
 
 0.902
LOC102360223
Cholesterol side-chain cleavage enzyme, mitochondrial; A cytochrome P450 monooxygenase that catalyzes the side-chain hydroxylation and cleavage of cholesterol to pregnenolone, the precursor of most steroid hormones. Catalyzes three sequential oxidation reactions of cholesterol, namely the hydroxylation at C22 followed with the hydroxylation at C20 to yield 20R,22R- hydroxycholesterol that is further cleaved between C20 and C22 to yield the C21-steroid pregnenolone and 4-methylpentanal. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate and reducing the se [...]
     
 0.901
LOC102357379
Sulfatase domain-containing protein.
 
  
  0.900
CYP7B1
Cytochrome P450 family 7 subfamily B member 1; Belongs to the cytochrome P450 family.
     
  0.900
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.